SERMORELIN
Sermorelin is the structurally truncated analog of Growth Hormone Releasing Hormone (GHRH). This product consists of the first 29 amino acids of the naturally occurring neurohormone produced in the hypothalamus. It is the most widely used member of the GHRH analogue drug class. This product can significantly promote the synthesis and release of growth hormone (GH) from cells in the pituitary gland, improving the serum concentrations of GH and subsequently insulin-like growth factor 1 (IGF-1) in humans. It is able to influence the concert of hormonal signals that affect GH secretion from the anterior pituitary including GHRH, somatostatin, and insulin like growth factor (IGF) and others.
The positive and negative opposing regulation of growth hormone by GHRH and somatostatin, respectively, creates a rhythmic- circadian pattern of GH secretion. Thus, modification of both pulse amplitude and frequency of GH secretion results from Sermorelin administration. After it stimulates the release of GH from the pituitary gland, it increases synthesis of IGF-1 in the liver and peripheral tissues.
SERMORELIN BENEFITS
- Increased lean body mass
- Body fat reduction
- Improved energy and vitality
- Increased endurance and strength
- Accelerated wound healing
- immune function benefits
- Improved cardiovascular function
- Improved sexual performance and libido
- sleep benefits
SERMORELIN SIDE EFFECTS
Side effects of Sermorelin are generally mild and may include flushing, dizziness, headache, or pain at injection site immediately after administration. These typically clear up quickly and may lessen significantly in severity with continued administration. A more common side effect is sleepiness due to its impact on GH and cortisol levels as well as slow wave sleep.
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